People who carry Emerade adrenaline pens have been told to replace them with an alternative brand because of concerns they might not work properly if they have been dropped.

What’s the problem?

On 9th May 2023, the Medicines and Healthcare products Regulatory Agency (MHRA) announced that some 300-microgram and 500-microgram Emerade auto-injectors might fail to activate or activate too early if they have been dropped. This means a dose of adrenaline would not be delivered.

How was the problem with Emerade pens discovered?

A design assessment by the manufacturer discovered the issue.

I carry an Emerade adrenaline pen or someone I care for carries an Emerade adrenaline pen, what should I do?

You need to replace your Emerade devices immediately.

Contact your GP and ask for a prescription for a different brand, either EpiPen or Jext. Pharmacists and pharmacy teams can also help with obtaining new prescriptions and dispensing new pens.

If you have children at school or nursery, make sure you replace any Emerade adrenaline pens they hold for your child.

“Keep hold of your Emerade pens until you receive a replacement.”

I have an Emerade 500 but EpiPen and Jext don’t have this dose. What should I do?

Consultant Paediatrician in Allergy, Professor Adam Fox says, “Studies have shown the level of adrenaline in the blood from an EpiPen 300 or Jext 300 is about the same as an Emerade 500, so don’t worry about replacing an Emerade 500 with either of these.”

What should I do with my Emerade adrenaline pens?

When you have received replacement pens, return your Emerade devices to a pharmacy.

What should I do if I have an allergic reaction and only have Emerade pens available?

The MHRA says “If an Emerade pen does need to be used, it should be pressed very firmly against the thigh. If this does not result in activation, the patient should immediately use their second pen.”  Remember to call 999 and explain it is anaphylaxis and you have used your pen but don’t have another one.

I’m not sure how to use other brands of adrenaline pens?

Each brand of adrenaline pen works differently so it’s important you familiarise yourself with how your new pens work.

The Allergy Team has instruction videos to help.

You can also ask your GP or pharmacist for support and EpiPen and Jext have instructions on their website.


How to use Jext

Picture: MHRA website

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